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SAMe ultimately plays a role in numerous methylation reactions catalyzed by methyltransferase enzymes including the synthesis of hormones, neurotransmitters, nucleic acids, proteins, and phospholipids (Mischoulon)

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Intranasal delivery, though less studied with Dihexa, would theoretically provide direct CNS access with minimal systemic exposure, potentially requiring the least frequent administration to maintain effective brain tissue concentrations

Para su sntesis precisa de un soporte de aminocidos esenciales, principalmente lisina y metionina adems de cido ascrbico, niacina, piridoxina y hierro, siendo su forma activa la L-carnitina